IRBESARTAN + HYDROCHLOROTHIAZIDE (HCTZ) 300 mg / 12.5 mg – 1 Box (28 Tablets)

Active Ingredients:

• Irbesartan 300 mg
• Hydrochlorothiazide (HCTZ) 12.5 mg

Pack Size: 28 tablets
Therapeutic Class: Angiotensin II Receptor Blocker (ARB) + Thiazide Diuretic

Description

This combination medicine contains irbesartan and hydrochlorothiazide (HCTZ) and is used to treat high blood pressure (hypertension) when a single medication alone does not provide adequate blood pressure control.

A well-known brand of this combination is CoAprovel.

Uses

• Hypertension (high blood pressure)
• Patients whose blood pressure is not adequately controlled with irbesartan alone
• Reduction of cardiovascular risks associated with uncontrolled hypertension

How It Works

Irbesartan blocks the effects of angiotensin II, relaxing blood vessels.

Hydrochlorothiazide (HCTZ) is a diuretic (“water tablet”) that helps the body remove excess salt and water through urine.

Together they provide a stronger blood-pressure-lowering effect than either medicine alone.

Dosage

• Usually 1 tablet once daily.
• Can be taken with or without food.
• Take at the same time each day.
• Follow your healthcare provider’s instructions regarding fluid intake and monitoring.

Common Side Effects

• Dizziness
• Fatigue
• Increased urination
• Headache
• Low blood pressure
• Changes in potassium, sodium, or other electrolyte levels

Important Precautions

⚠️ Do not use during pregnancy.

• Regular monitoring of blood pressure, kidney function, and electrolytes may be required.
• Use cautiously in patients with kidney disease, liver disease, gout, or diabetes.
• Inform your healthcare provider if you are taking potassium supplements, lithium, or other blood pressure medications.

Product Summary

Advantages

• Combines two proven blood pressure medicines in one tablet.
• Once-daily dosing.
• Often provides better blood pressure control than irbesartan alone.
• May reduce pill burden for patients taking separate medications.

Storage

• Store below 25–30°C.
• Protect from moisture and excessive heat.
• Keep in the original packaging.
• Keep out of reach of children.

Prescription Status: Prescription-only medicine.